Abstract: Objective: To introduce the Treatment Satisfaction Questionnaire for Medication (TSQM) to China, and to test its reliability and validity. Methods: Kidney transplant recipients were selected by convenience sampling from one transplantation follow-up center in one tertiary grade A hospital. Authorization was obtained from the original authors of the TSQM before the study. Results: A total of 218 valid questionnaires were obtained. The Cronbach's alpha of the whole scale was 0.707 and the internal consistency reliabilities of its four domains ranged from 0.847 to 0.961. The test-retest reliability of the whole scale and its four domains ranged from 0.930 to 0.995. Content Validity Index of TSQM was 1. The results of EFA showed that there were three common factors in TSQM, accounting for 73.256% of the total variance. Conclusion: The psychometric properties of Chinese version of TSQM proved to be good. TSQM is a concise tool to measure the satisfaction of patients who need strict medication therapy.