Abstract: Objective: To investigate the prevention effect of early-stage ambulation activity on postoperative complications of Total Hip Arthroplasty (THA). Methods: A multi-disciplinary team was established to implement early activity one day after surgery in patients with THA. Then the postoperative complications of patients who got THA in two different periods (before and after the new intervention) were compared. Results: After implementing early-stage activity, the incidence of Deep Vein Thrombosis (DVT) of lower extremity, the occurrence of constipation and prosthesis dislocation cases in observation group were less than those in the control group, and the occurrence of DVT and constipation were statistically different (P<0.05). The hip joint function recovery in the observation group was better than that in the control group, Harris scores in 15 days and 1 month after operation were statistically higher in the intervention group than those in the control group (P<0.05). Conclusion: Implementing early-stage activity after total hip arthroplasty can effectively reduce postoperative complications, accelerate the recovery of hip joint function and improve the quality of life after surgery.