Abstract: Objective: To evaluate the quality of clinical practice guidelines (CPGs) published relating to pediatric pain management, analyze and summarize the consensus of included recommendations from those guidelines, and to provide a reference for normatively developing pediatric pain management guidelines suitable for Mainland China. Methods: Relative guidelines published internationally from 2006 to 2016 were searched, then the quality of included guidelines was evaluated using AGREE II, and finally recommended levels of guidelines were given, repsectively. Results: A total of 60 guidelines were retrieved, of which 8 met the inclusion criteria. Average AGREE II scores in six domains (Scope and Purpose, Stakeholder Involvement, Rigour of Development, Clarity of Presentation, Applicability and Editorial Independence) were 81.25%, 53.82%, 46.88%, 76.74%, 44.27%, 42.19% separately. No A-class guideline was recommended. 7 guidelines were leveled as B-class (recommended after revise). 1 guideline was not recommended. Conclusion: These included guidelines were of general quality. The methodological rigor and reporting clarity of guidelines development would need further improvement urgently. Researchers need to develop guidelines for pediatric pain management which could include the latest and best evidences, so as to improve clinical practice quality in pediatric pain management.