Abstract: Objective: To normalize the management and prevention of noninvasive ventilator pressure ulcers, of elderly patients with terminal pneumonia. Methods: In accordance with the 2 cases of noninvasive ventilator pressure ulcers of elderly patients with terminal pneumonia, a comprehensive analysis of the causes was used to develop the usage specification and operation procedure, then compared nursing practice and the rate of noninvasive ventilator pressure ulcers before and after the implementation of measures. Results: There was significant difference in the nursing practice and the rate of pressure ulcer. Conclusion: In consideration of the particularity of noninvasive ventilator pressure ulcers of elderly patients with terminal pneumonia, to formulate the usage specification and operation procedure of noninvasive ventilator can effectively prevent noninvasive ventilator pressure ulcers, that is the focus of the elderly specialist clinical nursing work and the important measures to ensure the quality and safety of nursing for the aged.