Abstract: Objective: To observe and explore the effects of breast and acupoint massage on milk secretion and breast feeding at different time among women after delivery. Methods: Totally 150 women after delivery from July 2015 to February 2016 were recruited and randomly divided into 3 groups with 50 women in each group. The women in A, B, C group was given breast and acupoint massage at 2h, 12h, 24h after delivery, respectively. We compared postpartum serum prolactin levels, the first milk secretion time, 48 hours postpartum milk secretion, breast tenderness incidences and 30 days postpartum breastfeeding success rate among 3 groups. Results: The difference of the postpartum serum prolactin levels, among 3 groups was statistically significant (P<0.05). The difference of the first milk secretion time was statistically significant (P<0.05). The difference of the postpartum breast milk adequacy rate among three groups at 48h after delivery was statistically significant (P<0.05). However, the difference of the 30 days postpartum breast feeding success rate had no statistically significance (P>0.05). Significant difference was observed on postpartum breast pain within 48 hours in three groups and the difference of III degree breast tenderness incidence was statistically significant (P<0.05). Conclusion: Compared with 12h, 24h postpartum intervention, breast and acupoint massage 2h after delivery could promote earlier and more milk secretion, reduce incidence of breast tenderness.