Abstract: Objective: To investigate the current status of Peripherally Inserted Central Catheter (PICC) application among 147 tertiary Grade A hospitals in China. Methods: Totally 147 hospitals in 27 provinces (cities) were investigated from March to May, 2013 by a questionnaire designed by Chinese Nursing Society Intravenous Treatment Nursing Specialized Committee. Results: Among 147 hospitals, 146 (99.3%) have applied the technology of PICC. Ninety hospitals have applied the technology of Seldinger, and 101 hospitals have applied the technology of ultrasonic-guided Seldinger, accouting for 61.2% and 68.7%, respectively. However, only 89 hospitals set up PICC clinics. Imported, groshong and silicone catheter were used in 94.6%, 85.7% and 72.8% of the investigated hospitals, respectively. Totally 104 hospitals (70.7%)' disinfection scope was over 20cm. There was no regulation in 20.4% hospitals that blood return must be obtained to confirm that the PICC catheter was in the blood vessel before giving medication. Both of transparent semipermeable membrane (TSM)dressing and gause were widely used in 147 hospitals. Conclusions: More nursing needs should be met for the outpatients with PICC and the infection control should be stricter, and the method of confirming PICC catheter within the blood vessels is not standardized. Besides, differences between various catheters and the effects between different dressings should be explored in ordor to promote the development of infusion nursing.