Abstract: Objective: To investigate status of evidence-based practice in airway management among ICU nurses. Methods:A total of 347 ICU nurses from 3 hospitals and a training class for ICU nurses held by Chinese Nursing Association were recruited and investigated with self-designed questionnaire. Results: No one met all the requirements of airway management guidelines. Only 32.9% ICU nurses met the acquirements of airway humidification. Only 9.2% and 9.8% meet the acquirements of endotracheal suctioning and gasbag pressure monitoring. There was significant difference on correction rate for gasbag management among nurses from different departments. There was significant difference on correction rate for airway humidification among nurses got or did not get an ICU certificate (P﹤0.05). Conclusion: ICU nurses hold positive attitudes toward airway management guidelines wheras they are not frequently involved in evidence-based practice. Hospitals should provide evidence-based nursing education for ICU nurses and improve relevant resources so as to raise their awareness of EBN and improve their knowledge and skills.