Abstract: Objective: To improve the outpatients’ health care knowledge, to arouse the clinic nurses’enthusiasm on learning and working,to build a harmonious relationship between nurses and patients. Methods: According to the analysis of questionnaires filled by outpatients in combination with the patients’ characteristics and demands, we developed the contents of health lecture. Nurses carry out the lecture on their lunch break. Continuous quality improvement with activities is done according to the evaluation results and the needs of patients. Results: Not only the nurses improved professional knowledge and skills and teaching abilities, but also the patients enhance the awareness of prevention and treatment of diseases. The patient satisfaction rate of health lecture was 96.4%. Outpatients service has improved accordingly. Conclusion: Carrying out health lecture in outpatients is the bridge between nurses and patients, the expansion of the high quality nursing service, the good chance to improve the public science literacy, and the effective way to improve social and economic benefits.