Abstract: The incident rate of post-ICU cognitive impairment is relatively high in ICU survivors.Post -ICU cognitive impairment will severely affect the quality of life in patients and family members, increasing medical cost.The incidence of Post-ICU is a result of multiple factors and is difficult to be well prevented by using any single measure alone.The purpose of this article is to summarize the related factors and intervention measures in order to provice reference for clinical settings.