Abstract: Objective: To study the effect of applying feedforward control theory in nursing adverse events management.Method: In 2012, we used feedforward control theory in the management of nursing adverse events, and classified nursing hidden trouble events (type A events) and adverse events based on the original nursing adverse events classification. Then, we analyzed the number of reported adverse events and their impact on patients. Results: After using feedforward control in the management of nursing adverse events, 625 nursing hidden trouble events (type A events) were reported in 2012. While there were no type A events reported before 2012. In 2012, there were 44 type B and type C nursing adverse events reported, which were more than 36 cases and 39 cases reported in 2011 and 2010 respectively. Type C events accounted for 25.00% of all nursing adverse events in 2012, which was lower compared to those of 52.78% in 2011 and 61.54% in 2010. Conclusion: Application of feedforward control in management of nursing adverse events can enhance nursing adverse events reporting rate and reduce their impact on patients.