主管:国家卫生健康委员会
主办:国家卫生健康委医院管理研究所
中国科技核心期刊(中国科技论文统计源期刊)
中国科学引文数据库(CSCD)核心库期刊
《中文核心期刊要目总览》核心期刊

中国护理管理 ›› 2018, Vol. 18 ›› Issue (7): 983-987.doi: 10.3969/j.issn.1672-1756.2018.07.027

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器官移植患者免疫抑制剂服药依从性评估方法的研究进展

王春燕 杨小仙 陈思 杨梦雪 尹丽 周鸣鸣   

  1. 无锡太湖学院护理学院, 214064 江苏省无锡市
  • 出版日期:2019-01-07 发布日期:2019-01-07
  • 基金资助:
    荷兰“生命公寓”养老模式的产业化发展研究(17WURD009)

The research progress of immunosuppressive medication compliance assessment methods among organ transplant patients

  • Online:2019-01-07 Published:2019-01-07

摘要: 本文对器官移植患者服药依从性的评估方法进行综述,主要包括血药浓度测量法、电子监测法和问卷调查法。Basel评估量表和ITAS评估量表是目前国内外应用最广泛的评估工具。血药浓度监测和问卷调查相结合的综合研究法可以提高评估的敏感性,目前也被越来越多地应用。与其他慢性病患者相比,机体对移植器官的免疫排斥反应要求器官移植患者有较高的服药依从性,能更好地反映器官移植患者服药依从性的评估方法有待于进一步研究。

关键词: 器官移植;免疫抑制剂;服药依从性;评估方法;研究进展

Abstract: This paper reviewed the drug compliance assessment methods, including blood drug concentration measurement, electronic monitoring method and self-report method. The Basel assessment scale and the ITAS assessment scale in self-report method are the most widely used assessment tools. Comprehensive approach which combines the two research methods (e.g. the combination of blood drug concentration monitoring and questionnaire survey) can improve the sensitivity of assessment and is also used by more people. Compared with other chronic disease patients, the body's immune rejection of transplanted organs among organ transplant patients needs higher medication adherence. The assessment methods which could better reflect the organ transplant patients' medication compliance need further research.

Key words: organ transplantation; immunosuppressive agents; medication compliance; assessment methods; research progress