Abstract: Objective: To classify and organize the relevant evidence on the intervention of cognitive frailty in patients with atrial fibrillation, and provide a reference for clinical practice. Methods: According to the "6S" pyramid, we searched for literature on the intervention of cognitive frailty in patients with atrial fibrillation in Chinese and English databases from the establishment of the database to May 10, 2025. The quality of the included literature was evaluated, and the evidence was extracted and summarized. Results: A total of 13 articles were included, including 1 clinical decision, 2 guidelines, 3 expert consensus, 1 systematic reviews, and 6 randomized controlled studies. There were 21 pieces of evidence in total, covering 8 core themes: drug and interventional therapy, cognitive training, risk monitoring and assessment, exercise intervention, nutritional intervention, comorbidities and complications, family support, and internet support. Conclusion: This study summarizes the evidence on the intervention of cognitive frailty in patients with atrial fibrillation, providing scientific evidence-based basis for clinical medical staff.

Key words: atrial fibrillation; cognitive frailty; intervention measure; evidence-based nursing; evidence summary