Abstract: Objective: To analyze the latent profile characteristics of physical resilience in older adults with ischemic stroke, and to explore its influencing factors, in order to provide a reference for development of personalized intervention strategies. Methods: A total of 287 older adults with ischemic stroke in a tertiary grade A hospital in Hefei from November 2024 to July 2025 were enrolled through convenience sampling. The general information questionnaire, the Physical Resilience Instrument for Older Adults, the Short Physical Performance Battery, the Chronic Disease Self Efficacy Scale, and the Multidimensional Scale of Perceived Social Support were used for data collection. Latent profile analysis was used to identify the latent profiles of physical resilience, and multinomial Logistic regression was used to analyze the influencing factors. Results: The physical resilience score among older adults with ischemic stroke was 53.00±11.23, indicating an overall moderate level. Patients were categorized into three latent profiles: high resilience-positive belief integration (23.3%), moderate resilience-passive adaptation adjustment (44.3%), and low resilience-weak belief and coping (32.4%). Age, educational background, number of comorbidities, self-efficacy for chronic disease management, perceived social support, and simplified physical condition were identified as significant factors influencing physical resilience in older adults with ischemic stroke (all P<0.05). Conclusion: Significant group heterogeneity exists in physical resilience among older adults with ischemic stroke and the profiles are influenced by multiple factors. Healthcare providers can identify patients' resilience categories early to develop targeted, stratified intervention strategies, thereby enhancing overall resilience levels of the patients.

Key words: older adult; ischemic stroke; physical resilience; latent profile analysis; influencing factor