Abstract: Objective: To explore the effect of the national occupational health standard "Protection guideline for occupational exposure to bloodborne pathogens" (GBZ/T 213). Methods: Articles of study on the prevalence of occupational sharp injuries among nurses in China were retrieved and analyzed from CNKI, VIP, Wanfang, PubMed and Embase. Results: This pooling analysis focused on 90 literatures from 2000 to 2016 which consisted of collected data from 38,867 nurses of 319 hospitals across 26 provinces in China. The pooled incidence of sharp object injuries, needle stick and contaminated needle stick for nurses were up to 81.93%, 76.55%, 61.14% respectively. The average number of sharp object injuries, needle stick and contaminated needle stick were up to 3.14, 3.00, 2.02 episode per person per year, respectively. Compared with 2005-2009, the incidence of sharp object injuries, needle stick and contaminated needle stick during 2010 to 2016 were significantly decreased respectively. The 42.81% of the nurses accepted work safety and health training. 52.05% of the nurses were immunized with Hepatitis B vaccine. 23.67% of them wore gloves while nursing patients. 54.86% of the nurses who were injured could treat the wound properly, but only 14.00% of the episodes were reported. Conclusion: After the application of "Protection guideline for occupational exposure to bloodborne pathogens", occupational safety of clinical nurses has been improved. However the implementing of the standard needs to be emphasized to minimise the incidents. The comprehensive measures should be taken to achieve the maximum safety of the health professionals.