Abstract: Objective: To establish inpatient care risk assessment early warning monitoring biography reporting system, to evaluate, warn, monitor, and intervene, ultimately to reduce the occurrence of nursing adverse events. Methods: The hospital computer network was used to evaluate and data entry all newly admitted patients and all hospitalized patients. The system automatically screens high-risk inpatients and alerts nursing staff. According to the risk level, different nursing interventions are implemented accordingly. Closely monitor through hospital level, unit level and nursing quarters level, implement nursing interventions in advance. Results: The application of Inpatient care risk assessment early warning monitoring Biography reporting system for 1 year, nurses' qualified rate in the risk control of reporting number increased significantly (P<0.05); The number of reported nursing adverse events associated reduced significantly (P<0.05). Conclusion: The application of an Inpatient care risk assessment early warning monitoring Biography reporting system will improve nursing foresight significantly, and catch the great attention of nursing staff and managers, reduce the occurring of the nursing adverse events.