Abstract: Objective: To explore the correlation between quality of work life and social support among Intensive Care Unit (ICU) nurses. Methods: Totally 298 ICU nurses who came from 13 intensive care units of 6 tertiary hospitals in Guangdong province were recruited by convenience sampling during October 2014 to September 2015. The General information questionnaire, Quality of Nursing Work Life Scale (QNWLS) and Social Support Rating Scale (SSRS) were used. Results: Among the 298 nurses, the score of QNWL was (161.15±21.56), which was higher than the average level among tertiary hospitals in Guangdong province (P<0.01). The score of SSRS was (40.67±8.96), which was also higher than the average level among tertiary hospitals in Guangdong province (P<0.01). Pearson correlation analysis showed that quality of work life was positively correlated with social support (r=0.305). Conclusions: In tertiary hospitals of Guangdong province, the quality of work life and social support in ICU nurses are higher than the medium level.Social support was positively correlated with quality of work life work life.