Abstract: Objective: To investigate the current status and influencing factors of Post Traumatic Growth among the adolescents with chronic disease. Methods: Totally 194 adolescents with chronic disease were recruited by convenience sampling mechod. The Revised Posttraumatic Growth Inventory for Children (PTGI-CR), Perceived Social Support Scale(PSSS), and the Coping with disease (CODI) were used to measure the adolescents' posttraumatic growth and its influencing factors. Results: The total score of PTGI-CR was 15.54±7.23. The influencing factors included their age, gender,the parents' education level, family monthly income, coping style (self-consolation), and social support, which explained 26.3% of the variance. Conclusion: The PTG of the adolescents with chronic disease is in the low level. The nursing staff should find different ways to improve their post traumatic growth according to their different age, gender, the parents' education level, family monthly income, coping style(self-consolation), and social support.