Abstract: Objective: To investigate the ability of performing activities of daily living and nursing care workload for inpatient cholecystolithiasis patients. Methods: Totally 125 inpatient cholecystolithiasis patients were selected from a local hospital.The direct nursing hours and Barthel index were recorded. Results: We found negative correlation between the activities of daily living and direct nursing time. Barthel index is the lowest about (30.64±8.87) on the surgery date, but the direct nursing time is the highest about (61.67±8.39) min. Conclusion: The ability of performing activities of daily living is the significant factor influencing nursing workload, which should be taken into consideration in nursing staffing.