Abstract: Objective: To explore the applicability and feasibility of two-level triage system in our tertiary hospital outpatient visit management. Methods: The authors established two-level triage system based on the JCI outpatient safety management goal and homogeneity service, they defined the job description of clinic nurses, established outpatient safety management system,improved clinic environment, using outpatient triage software to support the two-level triage management. Results: The average waiting time decreased from 56.33 min to 40.95 min (P<0.001), the overall satisfaction for outpatient increased from 91.38% to 94.63% (P<0.001) after three-year practice. No one suffered sudden accident death in clinic. The rate of one clinic for one patient was 96.8%. Conclusion: The two-level triage system under JCI standard was safe and efficient for improving clinic service and outpatient satisfaction. It is an important means to increase outpatient service quality.