Abstract: Objective: To investigate the effect of the hospital customer relationship management (HCRM) in Refractive Center.Methods: Totally 150 patients who visited the Refractive Center from January to June, 2014 were selected as control group, they received routine nursing care. The experimental group also included 150 patients who came to the center from July to December,2014, and received HCRM service. Then, a self designed questionnaire was used to evaluate their satisfaction level. Results: The satisfaction levels of consultant process, medical information acquirement, and postoperative follow-up service in experimental group were higher than those in the control group (P<0.05). Conclusion: Application of HCRM system can provide a new experience on outpatient service, improve communication between patients and medical staff, and then enhance the hospital competitiveness in the medical business.