Abstract: Objective: To explore the practice effects of aggressive behavior management under Joint Commission International (JCI) standards among in-patients with schizophrenia Methods: We recruited 80 cases with aggressive behavior among schizophrenic patients and managed them under JCI standards for 3 weeks. We established risk management team,improved attack training, assessed systematically and comprehensively, and evaluated and improve the quality continuously.Results: Attack risk assessment indicated that we reduced risk grade III from 13.75% to 6.25% and risk grade IV from 11.25% to 3.75% after using JCI management. There were significant difference between the scores of each factor and total weighted score of Modified version of the overt behavior scale (MOAS), and the scores of each factor of Nurses Observation Scale for Inpatinent Evaluation (NOSIE) before and after intervention (P<0.01). Conclusion: JCI standard management could reduce the irritability and hostility of patients, improve their social interests, promote their social ability recovery, reduce their attack risk grade, reduce the occurrence of aggressive behavior, and guarantee nursing safety.