Abstract: Objective: To set up and evaluate the effectiveness of full time clinical assistant nurse in emergency joint clinic.Methods: We constructed the personnel allocation and responsibility of full time clinical assistant nurse in emergency joint clinic,and compared the average waiting time, adverse events rates, patient satisfaction, and clinic bed occupancy rate in ER in one year before and after implement. Results: The waiting time of grade III patients was shortened from 8.59±2.03 to 4.38±1.13 minutes,the adverse events rates was reduced by 36 cases, patient satisfaction was increased from 90.67% to 97.00%, clinic bed occupancy rate was fell from 1.13% to 0.92%, the differences were all statistically significant (P<0.05). Conclusion: The implement of full time clinical assistant nurse can optimize emergency medical order, facilitate dynamic observation of emergency patients, find condition change in time and ensure the safety of patients.