Abstract: Objective: To improve students’ comprehensive practice ability so as to meet requirements of the clinical nursing undergraduate by applying the theory of logical starting point to set and implement graduate practice courses for upgraded training students from the network school (experimental classes). Methods: Firstly, students accomplished the patient’s overall care based on their working task. Then they submitted a typical case nursing plan and completed the following practice courses according to the case. The contents of the project included: writing an individualized nursing care plan based on the changes of condition; conducting health education activities relating to the case; asking and answering questions for knowledge points involved in the case and evaluating the learning effects. Results: Totally, 18 students involved in the experimental class at the first session and 11 of them were qualified. The highest score of the comprehensive assessment was 89.00 and the median score was 71.75. Besides, the score of clinical typical cases, clinical nursing plans, multiple choices questions and analysis, giving a lecture by PPT or making a popular science video were 22.00, 10.50, 16.00, and 13.00,respectively. Conclusions: The setting and implementation of nursing practice courses based on the theory of logical starting point can promote students to solve clinical problems with scientific thinking methods and can help students learn to break up targets, and to make plans and improve learning goals by themselves.