Abstract: Objective: Analyze the risk factors for hospital acquired pressure ulcers in ICU patients. Method:Using self-designed information collection form and relative risk factors form, collect the clinical data pertaining ICU pressure ulcer from Oct of 2011 to Oct of 2013 in a tertiary Grade A hospital in Guangzhou, 468 patients were included,adopted Logistic Regression Analysis method to analyze ICU pressure ulcer risk factors. Result: Multiple Factors Logistic Regression Analysis revealed the following unique risk factors for ICU pressure ulcer: age, length of hospital stay, low Diastolic pressure, relatively low Albumin level, mechanical ventilation, incontinent of bowel and low Braden score (P<0.05).Conclusion: Interventions should be made on the timely fashion to high risk group, pay specific attention to the patients with following conditions: aging, lengthy hospital stay, low Diastolic pressure, low albumin level, mechnical ventilation,and incontinent of bowel. Also, pay attention to the accuracy and normalization of Braden Scale scoring.