Abstract: Objective: To evaluate the effect of anchored instruction in the course of Nursing Research for undergraduate nursing students. Methods: Anchored instruction was applied in the course of Nursing Research among 24 nursing undergraduates. The outcomes were evaluated by semi-structured interviews of 17 students. Results: Students reported that anchored instruction could improve their autonomous and active learning, facilitate their study of knowledge about research, guide their research ideas, and improve their comprehensive abilities. However, students also proposed some problems and suggestions in the implementation of anchored instruction, such as time pressure, insufficient communication among group members and different groups, unskilled application of knowledge. Conclusion: Compared with traditional instruction, anchored instruction has advantages in improving learning outcomes and students' comprehensive abilities, but also exists some problems. It is suggested to further optimize the implementation of anchored instruction.