Abstract: Objective: To investigate the current condition of Quality of Working Life and turnover intention among male nurses and analyze the correlation between them. Methods: Totally 628 male nurses were recruited by convenience sampling in 27 tertiary general hospitals in Guangdong province. They were investigated using the Quality of Nursing Work Life Scale (QNWLS) and Turnover Intention Scale. Results: Among the 628 male nurses recruited, the score of QNWL was (160.79±23.29). The score of turnover Intention was (15.80±3.35), and 83.3% of male nurses' turnover intention were high. Pearson correlation analysis showed that quality of working life was negatively correlated with turnover intention. Major influencing factors for male nurses to quit their jobs included working environment, career choice, work life balance, workload and affection for the department. Conclusions: Male nurses' quality of working life is fair. However,their turnover intention is relatively high. It is suggested that nursing administrators should improve male nurses' working environment, reduce workload and take other effective measures through the humanized management, in order to improve QWL of male nurses, to reduce the turnover intention of male nurses and to stabilize the team.