认知训练对糖尿病合并轻度认知障碍患者认知功能的影响

认知训练对糖尿病合并轻度认知障碍患者认知功能的影响

胡进黄金张艳王丽萍赖冰玉李蓓赵雪

中南大学湘雅二医院

出版日期:2015-09-25 发布日期:2015-09-25
基金资助:
美国雅礼协会贾氏社区联合项目（2013CC01）

Effects of cognitive training on type 2 Diabetes Mellitus patients with Mild Cognitive Impairment

Online:2015-09-25 Published:2015-09-25

摘要/Abstract

摘要： 目的：探讨认知训练对社区2 型糖尿病（T2DM) 合并轻度认知功能障碍（MCI) 患者认知功能的影响。方法：选取2014 年7 月至2015 年1 月长沙市某两个社区的T2DM 合并MCI 患者，对照组（40 例）接受社区常规护理，实验组（39 例)在此基础上进行认知训练。分别于干预前、干预3 个月末以及随访3 个月末使用蒙特利尔认知评估量表（MoCA) 北京版和简易智能状态检查量表（MMSE) 评估两组患者的认知功能。结果：两组患者MoCA 北京版、MMSE 得分的干预主效应、时间主效应、干预与时间交互效应间差异有统计学意义（P <0.05）；干预3 个月末及随访3 个月末实验组和对照组MoCA 北京版、MMSE 得分间差异有统计学意义（P <0.05）。实验组干预3 个月末及随访3 个月末MoCA 北京版、MMSE 得分较干预前升高（P <0.05）。干预后，实验组MoCA 北京版量表的视空间执行功能、抽象思维、延迟记忆领域的评分高于对照组（P <0.05）。结论：认知训练可有效改善社区T2DM 合并轻度MCI 患者的认知功能，值得在社区推广应用。

Abstract: Objective: To explore the effects of cognitive training on type 2 Diabetes Mellitus (T2DM) with Mild Cognitive Impairment (MCI) in community. Methods: The T2DM patients with MCI from two communities in Changsha city were selected as study subjects from July, 2014 to January, 2015, they were randomly divided into experimental group (39 cases) and control group (40 cases). The cases in control group received routine care of the community, while the cases in experimental group got 3-month cognitive training combined with routine care of the community. Cognitive functions of the two groups were evaluated prior to intervention, after intervention and after 3-month follow-up using Montreal Cognitive Assessment (MoCA)Beijing version and Mini Mental State Examination (MMSE). Results: There were significant differences in the main effects of intervention, the main effects of time and interaction between intervention and time on scores of MoCA Beijing version and MMSE between two groups, respectively (P<0.05). There was no significant difference in scores of MoCA Beijing version and MMSE between experimental group and control group before intervention (P>0.05). There were significant differences in scores of MoCA Beijing version and MMSE between experimental group and control group after intervention and 3-month followup(P<0.05). In experimental group, the scores of MoCA Beijing version and MMSE after intervention and follow-up were significantly higher than those before intervention, respectively (P<0.05). The scores of visuospatial abilities, abstraction and delayed memory of MoCA in the experimental group were statistically higher than control group after intervention (P<0.05).Conclusion: Cognitive training could significantly improve cognitive functions of T2DM patients with MCI in community.

胡进黄金张艳王丽萍赖冰玉李蓓赵雪. 认知训练对糖尿病合并轻度认知障碍患者认知功能的影响[J]. , 2015, 15(9): 1074-1078.