Abstract: Objective: To describe the feelings of patients at the beginning of the hemodialysis and provide the bases for individualized psychological care. Methods: The in-depth interview was conducted on 9 patients at the beginning of the hemodialysis individually. The data were analyzed by qualitative content analysis method. Results: The feelings of patients in the early stage of hemodialysis included negative emotions and positive emotions. The negative emotions were despair, anxiety, fear,anger or resistance, complaint, remorse. The positive emotions were accepted, hopeful and seeking information. Conclusion: The negative emotions of hemodialysis patients in the early stage are significant. We should understand the patients' needs and provide the individualized care for them.