Abstract: Objective: To reform Nursing Management curriculum and to cultivate practical nursing talents in the secondary vocational nursing education. Methods: The teachers from the school and the clinic integrated Nursing Management course.We added 8 hours of clinical probation courseware and 8 hours of clinical probation. Two classes were randomly divided into the experimental group and the control group. The experimental group was taught according to the integration curriculum of Nursing Management, and the control group was taught according to traditional methods. Result: After the curriculum reform, the satisfaction of teaching effects in the experimental group is higher than the control gruop (P<0.05). The clinical teachers' satisfaction toward the experimental group is higher than the control group (P<0.05). Conclusion: After the curriculum reform, the curriculum could satisfy the students' knowledge demand of adapting clinical work, solve the problem of classroom knowledge integrating with clinical practice, and provide valuable reference for cultivating practical nursing talents.