关键词: 机械通气；呼吸治疗；重症监护；康复；方案构建

Abstract: Objective: To construct an integrated respiratory therapy and rehabilitation program, and evaluate its curative effect in ICU patients with mechanical ventilation. Methods: Patients who were admitted to a tertiary grade A hospital in Anhui province for mechanical ventilation from January 2019 to December 2020 selected as research objects. The patients who implemented the individualized respiratory treatment and rehabilitation integrated program formulated by the team composed of doctors, respiratory therapists, rehabilitation therapists and nurses in 2020 were taken as the observation group, and the patients who received routine care of mechanical ventilation in 2019 were taken as the control group. Mechanical ventilation time, tracheal intubation time, 48h reintubation rate, Ventilator-Associated Pneumonia (VAP) incidence, delirium incidence, ICU acquired weakness incidence, early functional exercise rate, muscle strength after intervention and out of bed rate for the two groups were compared. Results: Totally 3124 mechanically ventilated patients were included, 1673 cases in the observation group and 1451 cases in the control group. Mechanical ventilation time, tracheal intubation time, 48h reintubation rate, VAP incidence, delirium incidence, and ICU acquired weakness incidence of the observation group were significantly lower than those of the control group, the differences were statistically significant (P<0.05). In the early functional exercise rate, muscle strength after intervention and the out of bed rate, the observation group was significantly higher than the control group, and the differences were statistically significant (P<0.05). Conclusion: This study shows that the integrated program of respiratory therapy and rehabilitation is scientific and feasible, the application of an integrated respiratory therapy rehabilitation program can shorten mechanical ventilation time and tracheal intubation time for mechanically ventilated ICU patients, reduce the 48h reintubation rate, the incidence of VAP and delirium.

Key words: mechanical ventilation; respiratory therapy; intensive care; rehabilitation; program construction