Abstract: Objective: To apply the best evidence on the prevention and management of fall in hospitalized children to clinical practice and evaluate its effect, so as to provide reference for improving the quality of care for hospitalized children. Methods: From June 2021 and November 2021, a total of 189 children and 23 nurses in the respiratory department of a tertiary-level hospital in Guangzhou were selected with convenience sampling method. The knowledge scores of nurses and caregivers, the implementation rate of the criteria, and fall rate were compared among the baseline review, the first review, and the second review. Results: For the data of nurses, the knowledge scores increased (P<0.05), and the implementation rates of each indicator in the two rounds of review were higher than those in the baseline, and the differences in some indicators were statistically significant (P<0.05). For the data of children, the incidence of fall was 6.5%, 1.7%, and 0 respectively in the three rounds of review, but the difference was not statistically significant (P>0.05). For the data of caregivers, the knowledge scores improved compared with that in the baseline (P<0.05). Conclusion: By developing the practice program for the prevention and management of falls in hospitalized children and applying it to clinical practice, the incidence of falls in hospitalized children can be reduced, the awareness level of nurses and caregivers can be improved, and the compliance of nurses to the implementation of the best evidence can be strengthened, and promoting the improvement of nursing quality.

Key words: hospitalized children; falls; best evidence; nursing; evidence-based practice