Abstract: Objective: To systematically search, screen, evaluate, and integrate relevant evidence on the management of orientation disorders in the elderly, and to form the best evidence summary, so as to provide evidence-based basis for medical staff and caregivers in the management of elderly people with disorientation. Methods: A comprehensive computerized search was conducted from relevant databases, guideline websites, and related professional websites at home and abroad from the inception of the database to April 2, 2024. The search included guidelines, best practices, expert consensus, evidence summaries, systematic reviews, Meta-analyses, and Randomized Controlled Trials (RCTs). Four researchers independently evaluated the quality of the guidelines, and two researchers independently evaluated the quality of the remaining literature, extracted, and summarized the evidence. Results: A total of 9 articles were included, including 1 clinical practice guideline, 2 expert consensus statements, 2 systematic reviews, and 4 RCTs, which altogether summarized 18 pieces of evidence on the prevention and management of time orientation disorders, spatial orientation disorders, person orientation disorders, and comprehensive interventions. Conclusion: This study summarizes the best evidence for the management of orientation disorders in the elderly. Medical staff and caregivers can timely promote the conversion and clinical application of evidence according to the actual situations and patients' willingness, thereby reducing the adverse effects of orientation disorders on their life and prognosis.

Key words: elderly; disorientation; evidence summary; evidence-based nursing