Abstract: Objective: To explore the effect of staging refined volume management in the elderly with Acute Heart Failure (AHF). Methods: Totally 127 hospitalized elderly with AHF were included in the Department of Cardiology of a tertiary grade A hospital in Jiangsu province from January 2019 to December 2020. According to the time of admission, there were 64 cases in the control group and 63 cases in the experimental group. Those in the control group were with routine nursing interventions; those in the experimental group were with three-stage refined volume management and nursing measures besides routine nursing intervention in the emergency, remission and stable period. The volume reduction and target achievement rate, the changes of Left Ventricular Ejection Fraction (LVEF) and B-type natriuretic peptide precursor (NT-proBNP), and were compared between the two groups on admission and 10 days after admission, the recurrence rate of AHF during hospitalization were compared between the two groups. Results: The volume reduction and target achievement rate, and the improvement of the LVEF in those of the experimental group were significantly higher than those in the control group after 10 days of admission (P<0.05), The NT proBNP and recurrence rate of AHF during hospitalization in the experimental group was significantly lower than those in the control group (P<0.05). Conclusion: The staging refined volume management is benefit to improve cardiac function and prognosis of elderly with AHF.

Key words: elderly; acute heart failure; refinement; volume management; volume reduction target