主管:国家卫生健康委员会
主办:国家卫生计生委医院管理研究所
中国科学引文数据库(CSCD)来源期刊
中国科技论文统计源期刊 中国科技核心期刊
《中文核心期刊要目总览》入选期刊

Chinese Nursing Management ›› 2024, Vol. 24 ›› Issue (6): 819-824.doi: 10.3969/j.issn.1672-1756.2024.06.004

• Special Planning • Previous Articles     Next Articles

Analysis of potential categories and predictive factors of the trajectory of Low Anterior Resection Syndrome in rectal cancer

HU Haiyan, SUN Jianan, ZHANG Qing, WANG Yanjun, WANG Meiling, WANG Quan, XU Yuting, HE Tingting, GUO Yuchen   

  1. Department of Gastrocolorectal Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, 130021, China
  • Online:2024-06-15 Published:2024-06-15
  • Contact: E-mail:sunjianan@jlu.edu.cn

Abstract: Objective: To explore the potential categories of Low Anterior Resection Syndrome (LARS) within 12 months after surgery in patients with mid-low rectal cancer and its predictive factors to provide reference for personalized health education to improve patients' life quality. Methods: A prospective study was used to select 116 patients who underwent sphincter-preserving surgery for mid-low rectal cancer from April 2021 to October 2022 as the study subjects. The socio-demographic and disease-related data of the patients were collected, and LARS scores were assessed 1 month, 3 months, 6 months, and 12 months after stoma surgery. The latent class growth model was used to identify postoperative LARS trajectories, and univariate analysis and Logistic regression analysis were employed to determine the predictive factors of different trajectory categories. Results: Two latent classes of LARS trajectories were identified in patients with mid-low rectal cancer, namely "mild symptom maintenance group" (35.3%) and "severe symptom relief group" (64.7%). There were statistically significant differences in the preoperative use of neoadjuvant therapy and whether pelvic floor rehabilitation therapy was performed during the preventive stoma period between the two groups (P<0.05). Conclusion: The incidence of LARS after surgery is relatively high in patients with mid-low rectal cancer, with symptoms lasting up to 6 months postoperatively or even longer in most patients. Group heterogeneity exists in LARS trajectories among different patient groups, and healthcare providers should refer to patients' LARS trajectory categories for personalized interventions to improve the outcomes of LARS.

Key words: rectal cancer; Low Anterior Resection Syndrome; trajectory; latent class; nursing; quality of life

CLC Number: R47;R197