Abstract: Objective: To evaluate the effects of Tai Chi on cognitive and psychological outcomes in older adults with Mild Cognitive Impairment. Methods: A computerized search was performed through PubMed, Embase, CENTRAL, CINAHL, Web of Science, the Chinese Biomedical Database, the China National Knowledge Infrastructure, VIP Journal Integration Platform, and Wanfang Med Online for Randomized Controlled Trials (RCTs) which studied the effects of Tai Chi on older patients with Mild Cognitive Impairment. Meta-analysis was performed by using RevMan 5.3 software. Results: Seven RCTs were included. Comparing to regular exercise or usual care, the memory [MD=0.37, 95%CI (0.13, 0.61), P<0.01], visuospatial function [SMD=0.57, 95%CI (0.23, 0.91), P<0.01] were improved in the aged with Tai Chi intervention. Conclusion: Tai Chi is efficacious in improving memory and visuospatial function in the aged with mild cognitive impairment, but cannot significant improve global cognitive functions, executive function, verbal fluency and depression.

Key words: Tai Chi; Mild Cognitive Impairment; aged; Meta-analysis