Abstract: Objective: In order to improve the effect of prevention and treatment of cancer in patients with hereditary colorectal cancer and their families, our hospital has established a hereditary colorectal cancer clinic based on physician-nurse collaboration for patients with hereditary colorectal cancer and their families. Methods: A hereditary colorectal cancer clinic based on physician-nurse collaboration was established and operated by a qualified chief physician with perfect training of colorectal surgery department and a clinical nurse specialist of oncology department. Qualification and training requirements of the chief physician and the nurse specialist were normalized and patients with risk of hereditary colorectal cancer and their families were considered as targeted people. The nurse made an appointment, inquired the family history, drew the family diagram, and collected the diagnosis and treatment data of the patients and their families while the director offered genetic counseling. A series of working systems and management methods were developed. Results: During the two and a half years of practice, 502 person times visited the clinic and family diagrams were collected and drew for 223 families. Besides, 120 families with hereditary colorectal carcinoma were diagnosed and offered follow-ups. Among the blood relatives of the 120 hereditary colorectal cancer patients, 52 were found to carry high-risk genes, 5 cases were diagnosed as colorectal cancer by colonoscopy, and 8 cases were polyps. Conclusion: With the help of the clinic, gene detection and tumor screening rate of high-risk relatives has been improved. Furthermore, early detection and early treatment of high-risk groups being promoted provides a practical basis for the construction of the management model of hereditary tumors.

Key words: colorectal cancer; hereditary; physician-nurse collaboration; clinic; genetic counseling; risk management