Abstract: Objective: To apply the evidence related to children's peripheral venous indwelling needles in the 8th edition of the "Practice Standards for Infusion Therapy" to clinical practice and evaluate its effectiveness. Methods: From July 2022 to March 2023, totally 24 department nurses and pediatric patients who were admitted to the Rheumatology and Immunology Department of a tertiary children's specialty hospital in Beijing and required indwelling needle infusion treatment were recruited. We adopted the evidence conversion model of Fudan University's Evidence Based Nursing Center and formulate policies based on clinical conditions. A survey questionnaire was used to investigate the awareness of nurses towards the evidence, and on-site observation and self-report were used to evaluate their compliance with the implementation of the evidence. Results: Application of evidence improved the awareness and compliance of nurses in puncture and maintenance of the evidence. Evidence was applied, which effectively prolonged the indwelling time (P<0.001) without increasing the incidence of indwelling needle phlebitis (P=0.205), significantly reduced venous treatment related costs (P<0.001), and thus reduced hospitalization costs. Conclusion: The application of evidence can improve the nursing quality of indwelling needles. Without increasing complications, the retention time of the indwelling needle can be prolonged, the number of punctures and hospitalization costs for the patient can be reduced , thereby reducing the workload of nurses and saving manpower.

Key words: peripheral venous indwelling needles; children; evidence based nursing; quality improvement