Abstract: Objective: To applicate the intelligent dispensing and delivery system in chemotherapy drugs and explore its effects, and provide a reference for ensuring medication safety and improving clinical work efficiency. Methods: We compared the time required for dispensing of chemotherapy drugs and the residual amount of drugs between nurse and robots by field observation method. The amount of chemotherapy drugs dispensed by manud and robots, the frequency of drug delivery between workers and robots were compared before and after the use of intelligent dispensing and delivery system. Results: The time required for manual dispensing of chemotherapy drugs was longer than that of robot dispensing (P<0.01), and the residual amount of drugs in manual dispensing was more than that of robot (P<0.01). The amount of chemotherapy drugs dispensed by robots was lower than that of manual (P<0.01). The amount of drugs delivered by robots per month was higher than that by workers (P<0.01). Conclusion: By applying the intelligent dispensing and delivery system for chemotherapy drugs, the accuracy and efficiency of drug administration can be improved, the frequency of contact between personnel and chemotherapy drugs can be reduced, which is beneficial for reducing the risk of occupational injury and is worthy of promotion and application.